Harrisburg Senators Roster & Staff
Harrisburg Transactions
| Date | Transaction |
| 08/09/22 | Harrisburg Senators released RHP Alberto Guerrero. |
| 08/09/22 | Harrisburg Senators released C Dondrei Hubbard. |
| 08/09/22 | LHP Carson Teel assigned to Harrisburg Senators from Rochester Red Wings. |
| 08/09/22 | RF Daniel Johnson assigned to Harrisburg Senators from FCL Nationals. |
| 08/05/22 | Harrisburg Senators released RHP Dakody Clemmer. |
| 08/05/22 | Harrisburg Senators released OF Jacob Rhinesmith. |
| 08/03/22 | Harrisburg Senators placed RHP Andrew Lee on the 7-day injured list retroactive to August 2, 2022. |
| 08/03/22 | Harrisburg Senators activated RHP Dakody Clemmer. |
| 08/03/22 | Harrisburg Senators activated RHP Dakody Clemmer. |
| 08/02/22 | 1B John Nogowski assigned to Rochester Red Wings from Harrisburg Senators. |
| 08/01/22 | Harrisburg Senators activated 2B Trey Harris. |
| 08/01/22 | 2B Trey Harris assigned to Harrisburg Senators. |