Inland Empire 66ers Roster & Staff
Inland Empire Transactions
| Date | Transaction |
| 08/09/22 | RHP John Swanda assigned to Tri-City Dust Devils from Inland Empire 66ers. |
| 08/05/22 | Inland Empire 66ers released RHP Jean Carlos Lucas. |
| 08/05/22 | RHP Max Gieg assigned to Inland Empire 66ers. |
| 08/05/22 | Inland Empire 66ers placed SS Werner Blakely on the 7-day injured list retroactive to August 4, 2022. |
| 08/05/22 | RHP Roman Phansalkar assigned to Inland Empire 66ers. |
| 08/05/22 | RHP Jared Southard assigned to Inland Empire 66ers. |
| 08/05/22 | Inland Empire 66ers released LHP Daniel Nunan. |
| 08/05/22 | RHP Stiward Aquino assigned to ACL Angels from Inland Empire 66ers. |
| 08/02/22 | Inland Empire 66ers activated RF Jadiel Sanchez. |
| 08/02/22 | RF Jadiel Sanchez assigned to Inland Empire 66ers. |