Iowa Cubs Roster & Staff
CHC Transactions
| Date | Transaction |
| 12/06/22 | LHP Brailyn Marquez assigned to Iowa Cubs. |
| 12/05/22 | Chicago Cubs signed free agent LHP Brailyn Marquez to a minor league contract. |
| 12/01/22 | RHP Connor Noland assigned to ACL Cubs. |
| 12/01/22 | RHP Luis Rujano assigned to ACL Cubs. |
| 12/01/22 | RHP Mason McGwire assigned to ACL Cubs. |
| 12/01/22 | LHP Branden Noriega assigned to ACL Cubs. |
| 12/01/22 | RHP Garrett Brown assigned to ACL Cubs. |
| 12/01/22 | AZL Cubs activated RHP Trey Lang. |
| 12/01/22 | C David Avitia assigned to ACL Cubs. |
| 12/01/22 | Chicago Cubs signed free agent RHP Adrian Santana to a minor league contract. |