South Bend Cubs Roster & Staff
South Bend Transactions
| Date | Transaction |
| 06/28/22 | South Bend Cubs activated C Casey Opitz from the 7-day injured list. |
| 06/24/22 | South Bend Cubs transferred LHP Riley Martin to the Development List. |
| 06/24/22 | LHP Adam Laskey assigned to South Bend Cubs from Myrtle Beach Pelicans. |
| 06/21/22 | South Bend Cubs activated RHP Bailey Reid. |
| 06/20/22 | RHP Yovanny Cruz assigned to South Bend Cubs from ACL Cubs. |
| 06/19/22 | South Bend Cubs placed C Casey Opitz on the 7-day injured list. |
| 06/18/22 | LHP Didier Vargas assigned to ACL Cubs from South Bend Cubs. |
| 06/14/22 | South Bend Cubs transferred RHP Bailey Reid to the Development List. |
| 06/14/22 | South Bend Cubs activated RHP Michael McAvene. |
| 06/14/22 | South Bend Cubs released IF Grayson Byrd. |
| 06/14/22 | South Bend Cubs sent RHP Tanner Jesson-Dalton on a rehab assignment to Myrtle Beach Pelicans. |
| 06/14/22 | 3B BJ Murray Jr. assigned to South Bend Cubs from Myrtle Beach Pelicans. |
| 06/14/22 | RHP Jeremiah Estrada assigned to Tennessee Smokies from South Bend Cubs. |
| 06/14/22 | RHP Gabriel Jaramillo assigned to South Bend Cubs from Tennessee Smokies. |
| 06/11/22 | South Bend Cubs sent RHP Michael McAvene on a rehab assignment to ACL Cubs. |
| 06/09/22 | RHP Jarod Wright assigned to South Bend Cubs from Myrtle Beach Pelicans. |
| 06/06/22 | South Bend Cubs sent RHP Yovanny Cruz on a rehab assignment to ACL Cubs. |
| 06/04/22 | South Bend Cubs placed RHP Bradford Deppermann on the 7-day injured list. |
| 06/03/22 | South Bend Cubs placed C Caleb Knight on the 7-day injured list. |
| 06/03/22 | South Bend Cubs activated C Caleb Knight. |
| 06/03/22 | SS Jake Slaughter assigned to Tennessee Smokies from South Bend Cubs. |